Discovery Projects - Grant ID: DP220103555

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP220103555

Funding Status
Active

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Funded Activity Summary

Regulatory roles of the RNA helicase DDX5 in male germline stem cells. This project aims to investigate the role of the RNA helicase DDX5 in regulating gene expression programs of male germline stem cells by utilising novel mouse models, stem cell culture and genome-wide analysis approaches. This project expects to generate new knowledge in the area of germline maintenance and adult stem cells using innovative in vivo and in vitro experimental systems. Expected outcomes of this project will include gain of substantial insight into molecular mechanisms underlying germline stem cell function and gene regulation within the male germline. This should provide significant benefits, including advancement of reproductive science and development of systems applicable for animal germline preservation and manipulation.

Funded Activity Details

Start Date: 12-07-2022

End Date: 11-07-2025

Funding Scheme: Discovery Projects

Funding Amount: $567,198.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination) | Gene Expression (incl. Microarray and other genome-wide approaches) | Cell Development, Proliferation and Death | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Cell Development, Proliferation and Death | Developmental Genetics (incl. Sex Determination) | Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics

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