Discovery Projects - Grant ID: DP220102997

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP220102997

Funding Status
Active

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Funded Activity Summary

Defining the antiviral effects of Wolbachia in Aedes aegypti mosquitoes. Mosquitoes that carry a bacterium called Wolbachia do not transmit human pathogenic viruses. These mosquitoes are being developed as a biocontrol tool to prevent mosquito-borne diseases. This project aims to define the molecular basis for virus inhibition by Wolbachia. Using unique biological tools including mosquitoes carrying different strains of Wolbachia that do or do not inhibit dengue virus, the project will define how Wolbachia modifies its host to create an antiviral state. The findings will provide insight into how viral pathogens can be suppressed in insect hosts. This may guide future viral disease intervention strategies for diverse areas afflicted by insect-borne viral disease, including human health and agriculture.

Funded Activity Details

Start Date: 01-03-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $460,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Virology | Genetically Modified Animals | Microbiology | Microbiology not elsewhere classified

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Infectious Diseases |

Other Keywords

Expanding Knowledge in the Biological Sciences | Genetically Modified Animals | Infectious Diseases | Microbiology | Microbiology not elsewhere classified | Virology

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