Discovery Projects - Grant ID: DP220102089

Funding Activity

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Funded Activity Summary

Investigating Wnt signaling during human nephron commitment and patterning. Aims: To use gene edited stem cell lines that display cell location, identity and cell state to map human kidney tissue formation in the laboratory. By monitoring how each cell responds to those around it across time and space, we will for the first time map the formation of kidney tissue in the dish. Significance: Understanding how stem cells form a tissue will help us to improve and control the process. This is key to advancing tissue engineering. Expected outcomes: The proposal will pioneer state-of-the-art imaging, gene editing and machine learning approaches, generating models of human development that are currently unavailable. Benefits: This understanding will guide the development of novel approaches to tissue engineering.

Funded Activity Details

Start Date: Start date not available

End Date: End date not available

Funding Scheme: Discovery Projects

Funding Amount: $454,560.00

Funder: Australian Research Council