Discovery Projects - Grant ID: DP220102018

Funding Activity

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Funded Activity Summary

Regulated muscle-based thermogenesis for body temperature regulation. Mammals maintain a constant core body temperature by generating heat in resting muscles in response to changes in the environmental temperatures. This project aims to show how the skeletal muscles that are closer to the body core contribute the majority of heat, how the muscles of the limbs have their heat generation curtailed as necessary, and how this is coordinated by the body in response to ambient temperature. Project outcomes include defining, for the first time, how heat generation in the muscles of the body is regulated. This should provide critical knowledge of mammalian evolution and ways to manipulate metabolism, which may provide ways to assist the production of meat by managing hypothermia and hyperthermia risk in agriculture.

Funded Activity Details

Start Date: 01-07-2022

End Date: 30-06-2025

Funding Scheme: Discovery Projects

Funding Amount: $608,390.00

Funder: Australian Research Council