Discovery Projects - Grant ID: DP220101681

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP220101681

Funding Status
Active

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Funded Activity Summary

The mechanistic basis of tropism in an insecticidal pore-forming toxin . This project aims to answer a fundamental question regarding the mechanism of a recently discovered family of insecticidal protein complexes - how do these pore-forming proteins recognise and target specific hosts? The project will use an innovative, cross-disciplinary approach to determine the mechanisms of cellular recognition and uptake on a molecular scale. These outcomes have the potential to influence the use of ABC toxins in many areas of biotechnology, delivering benefits including the development of new bioinsecticides for pest control and crop protection as well as in the development of bespoke protein delivery devices which may find use in biotechnological and therapeutic applications.

Funded Activity Details

Start Date: 01-08-2022

End Date: 31-07-2025

Funding Scheme: Discovery Projects

Funding Amount: $501,948.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling) | Crop and Pasture Protection (Pests, Diseases and Weeds) | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Control of Animal Pests, Diseases and Exotic Species in Farmland, Arable Cropland and Permanent Cropland Environments | Expanding Knowledge in the Biological Sciences |

Other Keywords

Bacteriology | Biochemistry and Cell Biology | Control of Animal Pests, Diseases and Exotic Species in Farmland, Arable Cropland and Permanent Cropland Environments | Crop and Pasture Protection (Pests, Diseases and Weeds) | Expanding Knowledge in the Biological Sciences | Structural Biology (incl. Macromolecular Modelling)

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