Discovery Projects - Grant ID: DP220101528

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP220101528

Funding Status
Active

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Funded Activity Summary

Synthetic leukocytes: bio-inspired DNA nanorobots powered by flow. Inspired by the way white blood cells roll along blood vessel walls, our goal is to build DNA nanorobots that roll along surfaces in flow. We take a synthetic biology approach to using biomolecules, such as DNA and proteins, to build functional particles and surfaces. To achieve this, we will combine our teams’ technological advances in DNA nanotechnology, plasma-activation for biomolecule immobilisation, and microfluidic devices. This project will contribute new methods for synthetic particle motion in flow and provide new insights into biomolecule interactions and motion. Ultimately, this will allow us to harness rolling for the delivery of synthetic nanorobots for detection and remediation in flow systems, such as the body.

Funded Activity Details

Start Date: 01-01-2023

End Date: 31-12-2025

Funding Scheme: Discovery Projects

Funding Amount: $578,178.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Functional Materials | Biochemistry and Cell Biology | Haematology | Synthetic Biology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Physical Sciences | Expanding Knowledge in Engineering | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Expanding Knowledge in Engineering | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Physical Sciences | Functional Materials | Haematology | Synthetic Biology

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