Discovery Projects - Grant ID: DP210103610

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP210103610

Funding Status
Active

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Funded Activity Summary

Role of Pasteurella surface polysaccharides in pathogenesis and immunity. Livestock infections cause major economic losses worldwide. The bacterium Pasteurella multocida causes multiple diseases in a range of livestock, including hemorrhagic septicaemia in cattle and fowl cholera in poultry. Two surface polysaccharide structures, capsule and lipopolysaccharide, are crucial for P. multocida to cause disease. Our data indicate that varying the amount/content of these structures also affects vaccine performance. This project aims to identify how the production of these P. multocida structures are controlled and if changes to these structures affect its ability to infect different animals/birds. Using this information, the project aims to develop state-of-the-art livestock vaccines with superior disease coverage.

Funded Activity Details

Start Date: 01-06-2021

End Date: 30-05-2024

Funding Scheme: Discovery Projects

Funding Amount: $737,180.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Veterinary Sciences | Veterinary Microbiology (excl. Virology) | Animal Protection (Pests and Pathogens)

ANZSRC Socio-Economic Objective (SEO)

Veterinary Biological Preventatives (e.g. Vaccines) | Expanding Knowledge in the Biological Sciences |

Other Keywords

Animal Protection (Pests and Pathogens) | Expanding Knowledge in the Biological Sciences | Veterinary Biological Preventatives (e.g. Vaccines) | Veterinary Microbiology (excl. Virology) | Veterinary Sciences

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