Discovery Projects - Grant ID: DP210103064

Funding Activity

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Funded Activity Summary

CD1C-LIPID-REACTIVE T CELLS. The immune system patrols our body examining molecules such as proteins and lipids that signal whether or not everything is ok. While protein recognition by the immune system is well understood, our knowledge of the fundamental features of lipid detection is poor. This project will investigate the detection of lipid molecules that are presented to the immune system in association with a molecule known as CD1c. The aims are to understand: 1. The cells that respond to these lipids; 2. The cellular receptors that bind to these lipids; 3. The types of lipids involved in this process. This work is essential for us to understand lipid-based immunology which is critical if we ultimately wish to harness this to improve human health.

Funded Activity Details

Start Date: 01-01-2021

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $489,715.00

Funder: Australian Research Council