Discovery Projects - Grant ID: DP210101957

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP210101957

Funding Status
Active

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Funded Activity Summary

Single-session Introduction of Mutations in Parallel Lines (SIMPL). This project aims to develop a novel method for markedly accelerating production of genetically modified mice, which are a key 'tool' for studying biological processes and diseases. The work plans to take CRISPR, the latest gene-editing technique, to the next level by developing a novel CRISPR-based method to generate different mouse strains with distinct variations of the same gene sequences, at a fraction of the present cost and time. This project should overcome a major barrier to studying gene function with unprecedented detail, thereby opening new avenues for future research into biological processes. Thus, the outcomes from this project should impact on the entire field of biomedical research, and advance Australia's biotech industry.

Funded Activity Details

Start Date: 01-01-2021

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $683,341.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medical Biotechnology | Medical Molecular Engineering of Nucleic Acids and Proteins | Biomaterials | Industrial Molecular Engineering of Nucleic Acids and Proteins

ANZSRC Socio-Economic Objective (SEO)

Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Neurodegenerative Disorders Related to Ageing |

Other Keywords

Biomaterials | Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified | Industrial Molecular Engineering of Nucleic Acids and Proteins | Medical Biotechnology | Medical Molecular Engineering of Nucleic Acids and Proteins | Neurodegenerative Disorders Related to Ageing

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