Discovery Projects - Grant ID: DP210101875

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP210101875

Funding Status
Active

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Funded Activity Summary

RNA structure prediction by deep learning and evolution-derived restraints. This project addresses the long-standing structure-folding problem of Ribonucleic acids (RNA) whose solution is essential for elucidating the roles of noncoding RNAs in living organisms. The proposed approach will detect hidden homologous sequences and enhance evolutionary covariation signals by developing new algorithms for search and smarter neural networks for deep learning. The project expects to generate new tools for structure-based probing of RNA evolutional and functional mechanisms. The outcomes should provide significant benefits by high-accuracy computational modelling of RNA structures that are difficult and costly to solve by current structural biology techniques but important for enabling biotech and clinical applications.

Funded Activity Details

Start Date: 01-01-2021

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $570,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Bioinformatics Software | Cognitive Science | Knowledge Representation and Machine Learning

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Information and Computing Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Bioinformatics Software | Cognitive Science | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Information and Computing Sciences | Knowledge Representation and Machine Learning

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