Discovery Projects - Grant ID: DP210101337

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP210101337

Funding Status
Active

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Funded Activity Summary

Deciphering the molecular mechanisms of parasite-host interactions. The completion of genome projects for several helminths of veterinary significance has provided novel insights into the fundamentals of helminth biology. One outcome is the identification of microRNAs, a subclass of small regulatory RNAs which in plants and mammalian cells control diverse biological processes at the posttranscriptional level. We have discovered the presence of helminth miRNAs within host cells with the ability to mimic mammalian miRNAs to modulate innate immune responses. This project will discover how helminths hijack the mammalian miRNA machinery to regulate host gene expression and thus support long-term infection. The outcomes will highlight new avenues for the control of these persistent worm infections.

Funded Activity Details

Start Date: 01-01-2021

End Date: 30-06-2024

Funding Scheme: Discovery Projects

Funding Amount: $567,949.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Veterinary Sciences | Veterinary Parasitology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Agricultural and Veterinary Sciences |

Other Keywords

Expanding Knowledge in the Agricultural and Veterinary Sciences | Veterinary Parasitology | Veterinary Sciences

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