Discovery Projects - Grant ID: DP210101280

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP210101280

Funding Status
Active

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Funded Activity Summary

Poly(amino acids) as immune stimulators. This project aims to develop nanoparticles built from natural hydrophobic amino acids as an immune stimulatory delivery system for peptide antigens. Currently available immune stimulants (adjuvants) are often toxic and/or are poorly chemically defined fragments of bacteria or toxins and vary from batch-to-batch. New adjuvants are in high demand; especially to facilitate the use of optimal, but weakly immunogenic, peptide antigens. It is expected that the proposed project will develop a novel efficient, safe and notably biodegradable self-adjuvanting delivery system that can be fully customised to match an antigen of choice. This foundational research should provide important advances for commercial immune stimulatory applications.

Funded Activity Details

Start Date: 01-07-2021

End Date: 30-06-2024

Funding Scheme: Discovery Projects

Funding Amount: $425,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies) | Proteins and Peptides | Medicinal and Biomolecular Chemistry | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Human Biological Preventatives (e.g. Vaccines) | Veterinary Biological Preventatives (e.g. Vaccines) |

Other Keywords

Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies) | Biologically Active Molecules | Human Biological Preventatives (e.g. Vaccines) | Medicinal and Biomolecular Chemistry | Proteins and Peptides | Veterinary Biological Preventatives (e.g. Vaccines)

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