Discovery Projects - Grant ID: DP210100362

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP210100362

Funding Status
Active

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Funded Activity Summary

Characterising O-linked glycosylation across Burkholderia. Protein glycosylation, the chemical addition of sugars to proteins, enables the augmentation of protein properties. Across the Burkholderia genus we have shown O-linked glycosylation is both conserved as well as essential for bacterial fitness. Yet, we have little understanding of how glycosylation modulates the proteome of this genus. This project aims to characterise the glycoproteomes of Burkholderia species and track the impact of glycosylation on both the proteome and protein stability. By understanding how glycosylation shapes the proteome we will gain a greater understanding of the role of bacterial glycosylation in Burkholderia physiology as well as how we may better utilise microbial glycosylation for glycoprotein production.

Funded Activity Details

Start Date: 23-03-2021

End Date: 23-03-2024

Funding Scheme: Discovery Projects

Funding Amount: $534,500.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Biochemistry and Cell Biology | Biochemistry and Cell Biology not elsewhere classified | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Human Biological Preventatives (e.g. Vaccines) | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Bacteriology | Biochemistry and Cell Biology | Biochemistry and Cell Biology not elsewhere classified | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Human Biological Preventatives (e.g. Vaccines) | Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

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