Discovery Projects - Grant ID: DP200103642

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200103642

Funding Status
Active

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Funded Activity Summary

Understanding how the heart becomes more efficient. The body demands that the heart function at utmost efficiency. Trabeculae – folds within the heart lumen – maximise blood flow, contribute to chamber development and form the electrical conduction network of the heart. Problems with trabeculae formation cause cardiomyopathy and arrhythmia and yet we do not understand its basic development. The project will investigate the earliest stages of when this tissue develops its identity and examine the signalling, genetic, cellular and extracellular cues required to instruct trabeculae to form in the heart. Findings from this research will revise our understanding of when and how trabeculae form and provide key information about how to grow and repair this important tissue.

Funded Activity Details

Start Date: 05-05-2020

End Date: 04-05-2023

Funding Scheme: Discovery Projects

Funding Amount: $470,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Developmental Genetics (incl. Sex Determination) | Cell Development, Proliferation and Death | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Cell Development, Proliferation and Death | Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Developmental Genetics (incl. Sex Determination) | Expanding Knowledge in the Biological Sciences | Genetics

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