Discovery Projects - Grant ID: DP200102962

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200102962

Funding Status
Active

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Funded Activity Summary

Next-Generation Multifunctional Nanoparticles for mRNA Transfection. This project aims to engineer a multifunctional nanoparticle platform tailored for mRNA delivery. An innovative assembly approach will be used to design nanoparticles with adjustable composition, asymmetry and surface topography. Uniquely, three functions will be integrated in one nanoparticle, with the goal to enhance transfection efficiency in target cells. This project expects to advance knowledge of mRNA transfection mechanisms, and determine how cell-type dependent particle-mRNA interactions correlate with the nanoparticle structure and delivery performance. Outcomes include a new family of functional materials with improved mRNA delivery performance over benchmark systems to facilitate and broaden the application of mRNA technology.

Funded Activity Details

Start Date: 19-06-2020

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $395,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nanomaterials | Biomedical Engineering not elsewhere classified | Functional Materials | Materials Engineering

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology |

Other Keywords

Biomedical Engineering not elsewhere classified | Expanding Knowledge in Technology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Functional Materials | Materials Engineering | Nanomaterials

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