Discovery Projects - Grant ID: DP200102737

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200102737

Funding Status
Active

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Funded Activity Summary

The RGG/RG motif as an RNA chaperone: advancing CRISPR-Cas RNA technology. This project investigates the way in which protein molecules interact effectively with RNA molecules and also aims to enhance the CRISPR-Cas13a system for RNA detection. Innovative approaches will be used to test the role of a particular protein motif, called the RGG/RG motif, in remodelling RNA structure and enhancing the Cas13a protein. This knowledge is expected to shift our understanding of protein-RNA interactions that are fundamental to almost every aspect of cell biology. The project is intended to benefit Australia through contributing to fundamental knowledge in the field, facilitating the development of new CRISPR-Cas biotechnologies for RNA detection and through the training of young researchers in frontier technologies.

Funded Activity Details

Start Date: 01-01-2020

End Date: 30-06-2023

Funding Scheme: Discovery Projects

Funding Amount: $420,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules | Medicinal and Biomolecular Chemistry | Biochemistry and Cell Biology not elsewhere classified | Immunological and Bioassay Methods

ANZSRC Socio-Economic Objective (SEO)

Diagnostic Methods | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology not elsewhere classified | Characterisation of Biological Macromolecules | Diagnostic Methods | Expanding Knowledge in the Biological Sciences | Immunological and Bioassay Methods | Medicinal and Biomolecular Chemistry

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