Discovery Projects - Grant ID: DP200101894

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200101894

Funding Status
Active

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Funded Activity Summary

Role of R-loops and double R-loops in genome organisation and transcription. The majority of our genome is converted to an extensive network of non-protein-coding RNA molecules (ncRNAs), but the function of these ncRNAs is unknown. This project aims to identify and determine the mechanism of action of nuclear ncRNA networks with a particular focus on nuclear ncRNAs that form RNA-DNA hybrids with the genomic DNA. These studies have the potential to lead to ground-breaking discoveries in our understanding of genome organisation and the mechanism of transcription control, and might provide an entirely new tool-box to manipulate genome function. This should provide significant benefits to efforts to develop innovative biotechnology and genome editing technologies in plants and animals.

Funded Activity Details

Start Date: 01-01-2021

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $500,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Epigenetics (incl. Genome Methylation and Epigenomics) | Gene Expression (incl. Microarray and other genome-wide approaches) | Genome Structure and Regulation | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Epigenetics (incl. Genome Methylation and Epigenomics) | Expanding Knowledge in the Biological Sciences | Gene Expression (incl. Microarray and other genome-wide approaches) | Genetics | Genome Structure and Regulation

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