Discovery Projects - Grant ID: DP200101668

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200101668

Funding Status
Closed

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Funded Activity Summary

Defining the origin of a cell lineage that surrounds and cleans the brain . The vertebrate brain is responsible for up to a quarter of the body’s metabolism, a metabolic load that produces large amounts of tissue waste and requires an efficient cleaning system. A recent discovery in zebrafish and preliminary data has uncovered a cell type surrounding the brain that derives from vasculature. These cells play fundamental roles in scavenging and clearing tissue wastes. The project aims to investigate the origins and control of this cell type in zebrafish and mouse brains. This will produce new knowledge in brain development, cellular composition, structure, function and evolution. Outcomes are expected to generate new approaches in stem cell biology, tissue engineering, regeneration and ageing of the brain.

Funded Activity Details

Start Date: 01-01-2020

End Date: 31-12-2022

Funding Scheme: Discovery Projects

Funding Amount: $648,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Developmental Genetics (incl. Sex Determination) | Genetics

ANZSRC Socio-Economic Objective (SEO)

Cardiovascular System and Diseases | Neurodegenerative Disorders Related to Ageing | Expanding Knowledge in the Biological Sciences |

Other Keywords

Cardiovascular System and Diseases | Developmental Genetics (incl. Sex Determination) | Expanding Knowledge in the Biological Sciences | Genetics | Neurodegenerative Disorders Related to Ageing

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