Discovery Projects - Grant ID: DP200101658

Funding Activity

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Funded Activity Summary

A Micro-Physiological System to Mimic Human Microbiome-Organ Interactions. This project aims to mimic gut microbiome-organ interactions by developing a microbial-gut coculture chip, which can reversibly interface with other organs-on-chips. This is achieved through the systematic integration of highly customisable biofabrication and microfluidic technologies. This project fills a critical technological gap in the availability of an animal-alternative system to investigate microbiome-host interactions, which will greatly complement existing meta-omics approaches. The deliverables include a proof-of-concept system validated for gut-liver axis as well as the creation of new knowledge and framework to assimilate design thinking and advanced manufacturing to elevate tissue engineering into physiology engineering.

Funded Activity Details

Start Date: 01-06-2020

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $390,000.00

Funder: Australian Research Council