Discovery Projects - Grant ID: DP200100991

Funding Activity

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Funded Activity Summary

Using Drosophila to analyse a master regulator of epithelial homeostasis. Aims: This proposal aims to use genetic and cell biological analysis of the vinegar fly, Drosophila, to identify the function of the grainyhead gene in intestinal regeneration. Significance: This gene is conserved in all animal species and appears to be a master regulator of epithelial tissue development but it is unclear how it can both influence stem cell maintenance and production of functional cell types. Expected outcomes: We will identify a new mechanism that governs tissue development, and introduce new imaging and genetic technologies to the Australian research community. Benefit: We expect potential economic and commercial interest in development of new gene analysis tools and biotechnological tissue manipulation applications.

Funded Activity Details

Start Date: 28-04-2020

End Date: 27-04-2023

Funding Scheme: Discovery Projects

Funding Amount: $625,000.00

Funder: Australian Research Council