Discovery Projects - Grant ID: DP200100914

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200100914

Funding Status
Active

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Funded Activity Summary

Structural Characterisation of the Type IX Secretion System. The Type IX Secretion System present in diverse bacteria of veterinary, agricultural, environmental and industrial importance enables effector proteins to be secreted and attached to the cell surface where they contribute to disease pathogenesis or degrade biopolymers of commercial interest. This project aims to determine the structure and assembly mechanism of this complex secretion nanomachine comprising 15 different proteins using state of the art microscopy. Knowledge of the structure will greatly enhance our understanding of secretion mechanisms and our ability to both inhibit the system to treat disease in animals or manipulate the system for industrial applications providing future economic and environmental benefits to our nation.

Funded Activity Details

Start Date: 01-12-2020

End Date: 30-11-2023

Funding Scheme: Discovery Projects

Funding Amount: $583,897.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Infectious Agents | Microbial Ecology | Microbiology | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Veterinary Biological Preventatives (e.g. Vaccines) | Expanding Knowledge in the Biological Sciences | Veterinary Pharmaceutical Treatments (e.g. Antibiotics) |

Other Keywords

Bacteriology | Expanding Knowledge in the Biological Sciences | Infectious Agents | Microbial Ecology | Microbiology | Veterinary Biological Preventatives (e.g. Vaccines) | Veterinary Pharmaceutical Treatments (e.g. Antibiotics)

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