Discovery Projects - Grant ID: DP200100892

Funding Activity

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Funded Activity Summary

Unlocking the secrets of the mitochondrion. This project aims to determine the frequency and mechanisms by which male-harming mutations (those with negative effects limited to males) accrue within the mitochondrial DNA. Theory predicts maternal inheritance of mitochondrial DNA will lead to accumulation of these mutations, but the real-world implications of this theory are unknown. Leveraging an innovative approach, this project expects to generate new knowledge into the causes of sex differences in physiology and health. Expected outcomes include insights that advance understanding of fundamental biological processes, and training of students. Expected benefits include strengthening of Australia’s research capacity, by setting the research agenda in this rapidly developing field.

Funded Activity Details

Start Date: 01-01-2020

End Date: 01-01-2025

Funding Scheme: Discovery Projects

Funding Amount: $437,000.00

Funder: Australian Research Council