Discovery Projects - Grant ID: DP200100646

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200100646

Funding Status
Closed

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Funded Activity Summary

A novel mechanism of host defence via macrophage extracellular traps. Animal health relies upon innate immune cells to rapidly detect invading microbes and induce inflammatory and antimicrobial responses to clear infection. Mechanisms of inflammation and immune defence are only partly understood. This project aims to elucidate a novel innate immune pathway (the inflammasome) that drives inflammatory cell death and antimicrobial defence. Using innovative multidisciplinary methods, this project will yield exciting new knowledge of mechanisms of inflammation and anti-microbial responses, and new paradigms for inflammasome action. Expected outcomes and benefits include high-impact publications, international collaboration, world-class training for young scientists, and new knowledge for future commercialisation.

Funded Activity Details

Start Date: 01-01-2020

End Date: 31-12-2022

Funding Scheme: Discovery Projects

Funding Amount: $565,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Signal Transduction | Cell Development, Proliferation and Death | Innate Immunity

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cell Development, Proliferation and Death | Expanding Knowledge in the Biological Sciences | Innate Immunity | Signal Transduction

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