Discovery Projects - Grant ID: DP200100341

Funding Activity

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Funded Activity Summary

Enabling Methodologies for the Synthesis of Biologically Active Compounds. This project seeks to establish flexible methods of chemical synthesis for creating new molecular scaffolds capable of achieving selective enzyme inhibition. The approach aims to exploit the vast and biologically-programmed structural diversity associated with natural products. Unique, small molecule organic compounds will be obtained that reveal details of the operation of key enzymes in bacterial and mammalian systems. Such new knowledge would allow for the design of highly selective therapeutic agents relevant to the treatment of a range of diseases including bacterial infections, diabetes and cancer. The high-end scientific training and privileged forms of matter arising from this work would provide major benefit to the biotech sector.

Funded Activity Details

Start Date: Start date not available

End Date: End date not available

Funding Scheme: Discovery Projects

Funding Amount: $490,000.00

Funder: Australian Research Council