Discovery Projects - Grant ID: DP200100250

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP200100250

Funding Status
Active

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Funded Activity Summary

Deciphering the regulatory principles of metazoan development. This proposal aims to elucidate how regulatory elements in the genome, known as enhancers, determine the identity and function of animal tissues. Currently, it is believed that enhancers cannot be traced across evolutionarily distant animals. The project uses novel concepts, computational and molecular approaches to identify deeply conserved enhancers. It further dissects the mechanism of function by proteomics and high-throughput genomics. The expected outcomes will overturn our current view on enhancer evolution and reposition our understanding of how enhancers are functionally encoded in the genome. The work is an important contribution to understanding cellular complexity and species evolution with wide-ranging impact in genetics.

Funded Activity Details

Start Date: 30-10-2020

End Date: 01-10-2024

Funding Scheme: Discovery Projects

Funding Amount: $715,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Evolution of Developmental Systems | Genome Structure and Regulation | Molecular Evolution | Genetics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Evolution of Developmental Systems | Expanding Knowledge in the Biological Sciences | Genetics | Genome Structure and Regulation | Molecular Evolution

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