Discovery Projects - Grant ID: DP190103187

Funding Activity

Website
https://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP190103187

Funding Status
Closed

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Funded Activity Summary

Potency and activity of Meso-Endothelial bipotent progenitors in vivo. This project aims to characterise a new stem cell population that can maintain both blood vessels and contribute to a variety of tissues whether fibrous, bone, fat or cartilage. Blood vessels comprise an inner endothelial layer and surrounding mesenchyme, are integral to many organs and constitute a unique system connecting different parts of the body. Despite their importance little is known about how they are maintained and how they contribute to the response to injury. Previous work has described several populations of stem cell capable of self renewal and repletion of the endothelium or the mesenchyme. This project will examine the potency of these different progenitors to give rise to each of these fates in homeostasis but also during sounding and bone formation. This will help define a unique population of stem cells capable of both vascular and mesenchymal repair.

Funded Activity Details

Start Date: 14-02-2019

End Date: 13-02-2022

Funding Scheme: Discovery Projects

Funding Amount: $350,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomedical Engineering not elsewhere classified | Medical Biotechnology | Biochemistry and Cell Biology not elsewhere classified | Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology not elsewhere classified | Biomedical Engineering not elsewhere classified | Expanding Knowledge in the Biological Sciences | Medical Biotechnology | Regenerative Medicine (incl. Stem Cells and Tissue Engineering)

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