Discovery Projects - Grant ID: DP190103045

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP190103045

Funding Status
Active

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Funded Activity Summary

Do sex steroids regulate tear lipid production in human meibomian glands? This project aims to determine whether production of tear film lipids by meibomian gland cells is regulated by sex steroids. The tear film is essential to eyesight. It protects and nourishes the eye surface to maintain transparency to enable light to reach the retina. To guarantee these functions, exquisite control of tear film composition is required, including the outer lipid layer. Sex hormones, including oestrogen, may control production of the lipid layer by meibomian glands in the eyelid, but this has not been confirmed in humans. This project aims to show whether meibomian glands produce sex hormones, which then control production of tear lipids. This new knowledge will improve our understanding of how the tear film maintains clear vision.

Funded Activity Details

Start Date: 01-09-2019

End Date: 31-08-2023

Funding Scheme: Discovery Projects

Funding Amount: $450,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Optometry and Ophthalmology | Vision Science |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Hearing, Vision, Speech and Their Disorders | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Hearing, Vision, Speech and Their Disorders | Optometry and Ophthalmology | Vision Science

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