Discovery Projects - Grant ID: DP190102499

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP190102499

Funding Status
Closed

Does something not look right? The information on this page has been harvested from data sources that may not be up to date. We continue to work with information providers to improve coverage and quality. To report an issue, use the .

Funded Activity Summary

Phosphoinositide regulation of lysosome reformation during autophagy. This project aims to investigate a new critical step in the autophagy pathway, autophagic lysosome reformation, a fundamental, evolutionarily conserved mechanism for cellular homeostasis. By combining gene function studies with advanced cellular imaging techniques, this project will investigate the dynamic membrane changes that drive this lysosome recycling pathway and how it is regulated by a hierarchical succession of specific enzymes. The expected outcome will be to re-define the archetypical autophagy pathway and characterise novel mechanisms by which it is controlled. This project will reveal new fundamental biological processes, and act as a framework for developing new imaging modalities and tools for studying autophagy.

Funded Activity Details

Start Date: 18-03-2019

End Date: 17-03-2022

Funding Scheme: Discovery Projects

Funding Amount: $475,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Protein Trafficking | Biochemistry and Cell Biology | Receptors and Membrane Biology | Signal Transduction

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Expanding Knowledge in the Biological Sciences | Protein Trafficking | Receptors and Membrane Biology | Signal Transduction

Related Links