Discovery Projects - Grant ID: DP190102464

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP190102464

Funding Status
Active

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Funded Activity Summary

Photodissociation mass spectrometry for lipidome analysis. This project aims to develop and apply novel bioanalytical mass spectrometry-based methods and workflows to illuminate the otherwise hidden structural diversity and molecular complexity of the lipidome. The structure of individual lipids define their specific biological functions. A major requirement of analytical methods employed for lipid analysis on a lipidome-wide scale, therefore, is to enable the detailed structural characterisation of the, potentially, tens of thousands of individual molecular lipid species that may be present within a sample of interest. This project will develop and optimise novel, ultraviolet photodissociation-tandem mass spectrometry methods which will be integrated within an automated lipidome analysis workflow, to enable comprehensive global lipidome profiling and to reveal the structural diversity of lipids involved in fundamental cellular signalling processes.

Funded Activity Details

Start Date: 08-02-2019

End Date: 31-12-2022

Funding Scheme: Discovery Projects

Funding Amount: $410,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Analytical Chemistry | Instrumental Methods (excl. Immunological and Bioassay Methods) | Analytical Biochemistry | Analytical Spectrometry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Analytical Biochemistry | Analytical Chemistry | Analytical Spectrometry | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Instrumental Methods (excl. Immunological and Bioassay Methods)

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