Discovery Projects - Grant ID: DP190102290

Funded Activity Summary

Atomic scale precision engineering of cell-material interfaces. This project aims to determine the molecular structure of the interface between novel peptide self-assemblies and cell membranes through x-ray diffraction and molecular simulation. The project will generate knowledge to enable atomic scale engineering of peptide nanomaterials, and exploitation of these materials to modulate cell responses. Expected outcomes include designed peptide nanostructures with specific chemical and physical cues to promote sustainable growth of desired cells, whilst inhibiting undesirable responses. These outcomes should provide benefits in terms of a practical toolkit for tailoring structure and function of peptide nanostructures and open up a new era in molecular design of smart biomaterials. This easily scalable, new materials platform will contribute to emerging high-value manufacturing industries in Australia.

Funded Activity Details

Start Date: 29-04-2019

End Date: 28-04-2022

Funding Scheme: Discovery Projects

Funding Amount: $500,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Theory and Design of Materials | Macromolecular and Materials Chemistry | Biomaterials | Structural Biology (incl. Macromolecular Modelling) |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology

Other Keywords

Biomaterials | Expanding Knowledge in Technology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Macromolecular and Materials Chemistry | Structural Biology (incl. Macromolecular Modelling) | Theory and Design of Materials

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