Discovery Projects - Grant ID: DP190102213

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP190102213

Funding Status
Closed

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Funded Activity Summary

A novel link between metabolism and host defence. This project aims to delineate how a protein modification that consists of the addition of a small sugar to cellular proteins, known as O-GlcNAcylation, provides a link between metabolism and complex cell functions. The model for these studies is a cell type of the immune system known as dendritic cells. Upon encountering pathogens these cells undergo metabolic changes that increase the rate of O-GlcNAcylation of proteins involved in immune responses, altering their function. This project will study how O-GlcNAcylation works and is regulated. The project expects to develop new technology and provide high-level training, increasing the competitiveness of the strategic biotechnology sector in Australia

Funded Activity Details

Start Date: 01-01-2019

End Date: 31-12-2021

Funding Scheme: Discovery Projects

Funding Amount: $520,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Immunology | Enzymes | Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Biochemistry and Cell Biology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cellular Immunology | Enzymes | Expanding Knowledge in the Biological Sciences | Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

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