Discovery Projects - Grant ID: DP190101969

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP190101969

Funding Status
Closed

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Funded Activity Summary

Mimicking the perivascular niche with boronolectin-based biomaterials. This project aims to address roadblocks in perivascular stem cell manufacturing by discovering novel mechanisms and materials that improve cell quality outcomes during extended culture. An innovative, interdisciplinary approach to biomaterials discovery, combining live cell-based screening of cell surface glycans, bio-inspired materials design and synthesis, and niche mimicry, will enable the discovery of cell surface glycan-mediated interactions that support long-term expansion and potency maintenance, and synthetic biomaterials that can mimic them. Significant benefits for stem cell researchers, manufacturers and end users are expected from the project and the application of this scalable biomaterial platform.

Funded Activity Details

Start Date: 27-03-2019

End Date: 26-03-2022

Funding Scheme: Discovery Projects

Funding Amount: $477,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Synthesis of Materials | Biomaterials | Biomedical Engineering

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Plastic Products (incl. Construction Materials) |

Other Keywords

Biomaterials | Biomedical Engineering | Expanding Knowledge in the Biological Sciences | Plastic Products (incl. Construction Materials) | Synthesis of Materials

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