Discovery Projects - Grant ID: DP190101486

Funded Activity Summary

Pluses and minuses of lipid mass spectrometry. This project aims to investigate the structural diversity of lipids. Lipids are among the most structurally diverse of all the biomolecules and thus deciphering their many functions requires bio-analytical technologies capable of uniquely identifying and quantifying individual molecules in a milieu of many thousands of analogues. Mass spectrometry is the pre-eminent technique for contemporary lipid analysis but is challenged by the preference of certain lipids to ionise with a polarity that affords sensitive detection but does not permit detailed structure elucidation. This project will develop advanced instrumentation capable of on-demand polarity switching of ionised lipids such that the detection and interrogation of molecular structure can take place in the optimal charge state.

Funded Activity Details

Start Date: 01-01-2019

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $655,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Analytical Chemistry | Medical Biochemistry: Lipids | Analytical Biochemistry | Analytical Spectrometry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences |

Other Keywords

Analytical Biochemistry | Analytical Chemistry | Analytical Spectrometry | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Medical and Health Sciences | Medical Biochemistry: Lipids

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