Discovery Projects - Grant ID: DP180103661

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP180103661

Funding Status
Closed

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Funded Activity Summary

Fine control of nucleic acid transport using cyclic peptide nanotubes. This project aims to develop new technology to enhance the transport of nucleic acids (DNA or RNA) across biological membranes, and to facilitate the delivery of nucleic acids into mammalian cells. Elaborate transport mechanisms have emerged by evolution of viruses but the use of viruses for therapeutic purposes presents safety challenges. This project aims to enhance the efficiency of synthetic nucleic acid delivery systems, making use of novel biocompatible materials which assemble into controlled three-dimensional structures, offering more control over membrane interactions. The project is expected to provide a new platform of smart materials which could be developed for biomedical applications in the future.

Funded Activity Details

Start Date: 01-01-2018

End Date: 31-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $501,024.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Pharmacology and Pharmaceutical Sciences | Pharmaceutical Sciences | Nanobiotechnology | Nanochemistry and Supramolecular Chemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Nanobiotechnology | Nanochemistry and Supramolecular Chemistry | Pharmaceutical Sciences | Pharmacology and Pharmaceutical Sciences

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