Discovery Projects - Grant ID: DP180103426

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP180103426

Funding Status
Closed

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Funded Activity Summary

Movement of mitochondria between cells. This project aims to characterise how mitochondria move between cells into grafted cells with dysfunctional mitochondrial function. How mitochondria reach the acceptor cell and how they move from the donor cell is not known. The project will use a 'bottom-up' approach, starting from a reconstituted system, via in vitro, co-culture stage to a relevant biological model, increasing complexity and biological relevance. It will document that the process of mitochondrial intercellular movement is dependent on intercellular bridges and a specific mobility system. The project is of high relevance for cell biology.

Funded Activity Details

Start Date: 22-02-2018

End Date: 31-12-2021

Funding Scheme: Discovery Projects

Funding Amount: $443,389.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Medicinal and Biomolecular Chemistry | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biologically Active Molecules | Expanding Knowledge in the Biological Sciences | Medicinal and Biomolecular Chemistry

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