Discovery Projects - Grant ID: DP180102987

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP180102987

Funding Status
Closed

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Funded Activity Summary

How auto-transporter proteins mediate bacterial interactions. This project aims to investigate the structure-function relationships that underpin key auto-transporter roles in bacterial cell adhesion, aggregation and biofilm formation. Auto-transporter proteins are extremely common in bacteria where they play a central role in controlling bacterial interactions with other bacteria, with human cells, and with surfaces. This project will define the molecular mechanisms underlying these processes. This will have significant benefits, such as providing the basis for the development of approaches to block auto-transporter functions that contribute to the establishment of persistent and difficult to treat bacterial infections.

Funded Activity Details

Start Date: 01-01-2018

End Date: 31-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $477,446.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Structural Biology (incl. Macromolecular Modelling) | Microbiology | Microbiology not elsewhere classified | Bacteriology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Infectious Diseases |

Other Keywords

Bacteriology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences | Infectious Diseases | Microbiology | Microbiology not elsewhere classified | Structural Biology (incl. Macromolecular Modelling)

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