Discovery Projects - Grant ID: DP180101897

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP180101897

Funding Status
Closed

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Funded Activity Summary

Fluorescent sensing of the intracellular redox environment. This project aims to develop chemical approaches to measure the redox environment of living cells. Oxidation and reduction (redox) reactions are crucial for cellular health and disease and the redox status of cells is known to affect their response to external stress, but surprisingly there remains no way of efficiently and accurately determining cellular redox environments. In this project, new fluorescent redox sensors will be designed and incorporated into assays that enable high-throughput analysis of cell types. These fundamental chemical and biochemical studies could provide the basis of future research into how redox environment can be used as a predictor for disease and therapeutic outcomes.

Funded Activity Details

Start Date: 01-01-2018

End Date: 31-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $362,045.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Inorganic Chemistry | Bioinorganic Chemistry | Biologically Active Molecules

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Bioinorganic Chemistry | Biologically Active Molecules | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Inorganic Chemistry

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