Discovery Projects - Grant ID: DP180101807

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP180101807

Funding Status
Active

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Funded Activity Summary

Laws of attraction and repulsion: a novel family of bacterial chemo-sensors. This project aims to reveal the structural basis for the abilities of a newly characterised, widespread family of chemotaxis receptors to sense and distinguish between attractants and repellents. Many bacteria are motile. Controlling the movement of bacterial populations requires understanding of their chemosensory mechanisms. It is anticipated that this work will generate significant new knowledge in the field of signalling biology that will drive the discovery of novel chemo-effectors and the redesign of receptor specificity. Innovative use of this knowledge could be the development of new classes of repellents that are not toxic. These could be used as a means to prevent infections caused by bacterial build-up on implanted medical devices.

Funded Activity Details

Start Date: 01-01-2018

End Date: 31-12-2022

Funding Scheme: Discovery Projects

Funding Amount: $429,536.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Receptors and Membrane Biology | Structural Biology (incl. Macromolecular Modelling) | Biological Physics

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Physical Sciences | Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Biological Physics | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Physical Sciences | Receptors and Membrane Biology | Structural Biology (incl. Macromolecular Modelling)

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