Discovery Projects - Grant ID: DP180101804

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP180101804

Funding Status
Closed

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Funded Activity Summary

New synthetic strategies to small cyclic peptides. This project aims to invent new synthetic strategies that enable chemical manipulation of small cyclic peptides, a promising class of biologically active molecules with high metabolic stability. Combining theory and practice, this project will develop novel acyl transfer reactions that will allow traceless, site-selective, ring expansion and contraction of small cyclic peptides. This project will result in new synthetic methodology that will simplify the synthesis of an important class of small drug-like molecules. This will provide significant benefits, such as a breakthrough in the synthetic approach to small cyclic peptides, which will strengthen Australia’s international standing in peptide research and provide new strategies for translation to the growing biotechnology industry.

Funded Activity Details

Start Date: 01-01-2018

End Date: 31-12-2021

Funding Scheme: Discovery Projects

Funding Amount: $396,610.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Physical Organic Chemistry | Organic Chemistry | Organic Chemical Synthesis

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences |

Other Keywords

Expanding Knowledge in the Chemical Sciences | Organic Chemical Synthesis | Organic Chemistry | Physical Organic Chemistry

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