Discovery Projects - Grant ID: DP170104749

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP170104749

Funding Status
Closed

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Funded Activity Summary

Background-free imaging of single membrane-receptors with nanophosphors. This project aims to develop nanophosphor beacons and real-time, ultrahigh-sensitivity functional imaging to provide a picture of the brain. Time-gated detection microscopy will give these nanophosphors a superior optical contrast. The nanophosphors’ antibody-targeting will image single AMPA membrane receptors in their full biological context, crucial to understanding neuronal signalling. Simultaneous imaging of receptor trafficking and activity in neurons will help to uncover details of the dynamic activity in the brain. This technology is expected to help understand the inner workings of the brain and provide insights into its functioning.

Funded Activity Details

Start Date: 01-01-2017

End Date: 31-12-2021

Funding Scheme: Discovery Projects

Funding Amount: $356,500.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Nanophotonics | Nanotechnology | Nanobiotechnology | Biological Physics |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in Technology

Other Keywords

Biological Physics | Expanding Knowledge in Technology | Expanding Knowledge in the Biological Sciences | Nanobiotechnology | Nanophotonics | Nanotechnology

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