Discovery Projects - Grant ID: DP170104408

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP170104408

Funding Status
Closed

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Funded Activity Summary

Does muscle contribute to the maintenance of vitamin D status in winter? This project aims to test the mechanism by which vitamin D status is maintained in winter when input is low. The long half-life in blood of the vitamin D metabolite, 25-hydroxyvitamin D [25(OH)D], maintains an adequate vitamin D status over winter, when sunlight, which produces vitamin D in skin, is reduced. From preliminary data in sheep and mice, this project proposes that skeletal muscle, not fat, stores vitamin D. This project will test this hypothesis in sheep, cultured muscle cells and in transgenic mice. The project will confirm whether the processes identified in skeletal muscle contribute to the maintenance of vitamin D status, and identify ways of enhancing this process.

Funded Activity Details

Start Date: 01-01-2017

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $392,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Animal Physiology - Systems | Systems Physiology | Physiology

ANZSRC Socio-Economic Objective (SEO)

Environmentally Sustainable Animal Production not elsewhere classified | Expanding Knowledge in the Biological Sciences | Health Related to Specific Ethnic Groups |

Other Keywords

Animal Physiology - Systems | Environmentally Sustainable Animal Production not elsewhere classified | Expanding Knowledge in the Biological Sciences | Health Related to Specific Ethnic Groups | Physiology | Systems Physiology

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