Discovery Projects - Grant ID: DP170103093

Funding Activity

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Funded Activity Summary

Surveillance of the mechanisms controlling proteome foldedness. This project aims to measure how cells keep the proteome folded. Cells have extensive quality control networks to govern synthesis, folding and transport of every protein but the buffering capacity of this system is not definable. This capacity is needed to understand how problems arise in managing proteome foldedness, a central feature of human diseases and biotechnology and synthetic biology applications that need cell-based production of engineered proteins such as hormones and antibodies. The outcomes are expected to provide basic knowledge of this fundamental process and provide biosensors and screening methods for use in health and biotechnology industries.

Funded Activity Details

Start Date: 01-01-2017

End Date: 30-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $466,500.00

Funder: Australian Research Council