Discovery Projects - Grant ID: DP170102402

Funding Activity

Website
https://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP170102402

Funding Status
Closed

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Funded Activity Summary

How membrane-sensing proteins regulate synaptic vesicle endocytosis. This project aims to elucidate the molecular basis of how membrane-sensing proteins regulate synaptic vesicle endocytosis in mammalian central neurons. Nerve cells’ ability to transmit cellular information to one another is important for normal brain function. Efficient communication between neurons through sustained neurotransmitter release relies on the continuous supply of synaptic vesicles in presynaptic nerve terminals. Key to this process are membrane dynamics during synaptic vesicle retrieval, but the precise underlying mechanisms are not well understood. The intended outcome of this project is insights into the molecular mechanisms of synaptic transmission, the fundamental process of brain function, increasing understanding of physiological processes such as muscle movement, vision, hearing, touch, learning and memory.

Funded Activity Details

Start Date: 01-01-2017

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $418,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System | Protein Trafficking | Biochemistry and Cell Biology | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Cell Neurochemistry | Cellular Nervous System | Expanding Knowledge in the Biological Sciences | Protein Trafficking

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