Discovery Projects - Grant ID: DP170101850

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP170101850

Funding Status
Closed

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Funded Activity Summary

Molecular basis for control of DNA transcription of housekeeping genes. This project aims to understand how 90 per cent of all eukaryotic genes are regulated. The development of a multicellular organism needs thousands of different messenger RNAs, at exactly the right time, in the right set of cells and in the right amount, creating a need for stringent regulation of gene expression. The data generated by the project will show how a massive protein complex of ~50 individual gene products—the general transcription machinery—identifies a gene’s start site, recruits RNA polymerase II and prepares it for transcription of the genetic code. The project is expected to reveal the molecular basis of a process that is as important for flowering in plants as it is for embryonic development in metazoans.

Funded Activity Details

Start Date: 01-01-2017

End Date: 31-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $399,500.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Characterisation of Biological Macromolecules | Biochemistry and Cell Biology | Structural Biology (incl. Macromolecular Modelling)

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Biochemistry and Cell Biology | Characterisation of Biological Macromolecules | Expanding Knowledge in the Biological Sciences | Structural Biology (incl. Macromolecular Modelling)

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