Discovery Projects - Grant ID: DP170101453

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP170101453

Funding Status
Closed

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Funded Activity Summary

Quantifying reactive species in biological systems. This project aims to discover how reactive oxygen and nitrogen species affect cell function, oxidative stress and cell dysfunction. The underlying mechanisms are often unknown because methods to measure reactive species and associated oxidative stress are inadequate. This project will synthesise multi-purpose probes and combine these with mass spectrometry-based analytics and mathematical modelling. This will allow concurrent quantification of reactive species in specific cellular compartments in a time-dependent manner that reflects their intricate interaction and metabolism in complex biological systems. This project could clarify whether and how reactive species affect cell function, ageing and disease.

Funded Activity Details

Start Date: 30-06-2017

End Date: 30-06-2020

Funding Scheme: Discovery Projects

Funding Amount: $371,000.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biochemistry and Cell Biology | Analytical Biochemistry |

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences

Other Keywords

Analytical Biochemistry | Biochemistry and Cell Biology | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Medical and Health Sciences

Related Links

ACN 633 798 857