Discovery Projects - Grant ID: DP170100181

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP170100181

Funding Status
Closed

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Funded Activity Summary

Protein design. This project aims to design binding specificity in proteins in a rational way. Extending the existing repertoire of protein specificity using engineering principles should harness the catalytic power and high binding affinities of natural proteins. By building upon protein design algorithms, this project will develop biosensors for neurotransmitters and specialist enzymes to incorporate unnatural amino acids. It will iteratively improve the designs and algorithms by computational and experimental characterisation. The outcomes should address the long-standing need in synthetic biology for a facile route to designer proteins

Funded Activity Details

Start Date: 01-01-2017

End Date: 31-12-2019

Funding Scheme: Discovery Projects

Funding Amount: $485,500.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Biomolecular Modelling and Design | Biochemistry and Cell Biology | Synthetic Biology

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Chemical Sciences | Expanding Knowledge in the Biological Sciences | Manufacturing not elsewhere classified |

Other Keywords

Biochemistry and Cell Biology | Biomolecular Modelling and Design | Expanding Knowledge in the Biological Sciences | Expanding Knowledge in the Chemical Sciences | Manufacturing not elsewhere classified | Synthetic Biology

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