Discovery Projects - Grant ID: DP160104980

Funding Activity

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Funded Activity Summary

Developmental genetics of malaria parasites. This project aims to improve our understanding of malarial genetics. The sexual cycle of malaria parasites occurs in mosquitoes. After sex, parasite progeny multiply to form infective spores that are injected into people by mosquito bite. Development of male and female malaria parasite gametes and their fusion to produce a diploid zygote are well understood, but the subsequent process of meiosis, development of a cyst stage and the sporogenic process to create haploid progeny for new infections are poorly understood in molecular genetic terms. The project aims to dissect the unique genetics of these insect stages using a rodent malaria model to generate crosses of different malaria parasite lines to determine when recombination takes effect.

Funded Activity Details

Start Date: 01-01-2016

End Date: 30-07-2017

Funding Scheme: Discovery Projects

Funding Amount: $486,700.00

Funder: Australian Research Council