Discovery Projects - Grant ID: DP160104359

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160104359

Funding Status
Closed

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Funded Activity Summary

Understanding the molecular mechanisms regulating neuronal fusion. Neurons are tightly connected individual cells that communicate through chemical and electrical signals, and this project aims to discover the key molecules that allow these cells to remain as individual units without fusing with each other. The nervous system, unlike other tissues, is made of discrete individual cells, connected by chemical and electrical synapses but not by cytoplasmic continuity. However, how this is achieved and how neurons maintain their individuality during development, remodelling and ageing is unknown. The project aims to address this gap using a genetic approach and the nematode Caenorhabditis elegans as an experimental system. The results may provide insights into how the nervous system develops and functions.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2020

Funding Scheme: Discovery Projects

Funding Amount: $517,400.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Cellular Nervous System | Neurosciences

ANZSRC Socio-Economic Objective (SEO)

Expanding Knowledge in the Biological Sciences |

Other Keywords

Cellular Interactions (incl. Adhesion, Matrix, Cell Wall) | Cellular Nervous System | Expanding Knowledge in the Biological Sciences | Neurosciences

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