Discovery Projects - Grant ID: DP160104342

Funding Activity

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Funded Activity Summary

Mathematical modelling of the dynamics of multi-layered biological tissues. The project intends to develop a mathematical model of the basic mechanisms that determine the self-organisation of cells into complex tissues during the development of the embryo. Tissue function requires a non-trivial tissue architecture often composed of multiple cell layers which exhibit a remarkable capacity for renewal and defect correction. A cardinal part of embryonic development involves robust shaping of multi-layered tissue morphologies. The project plans to use mathematical models to determine how complex, three-dimensional structures arise from adaptive multicellular biomechanical interactions. It plans to develop a novel computational modelling framework to represent and analyse such systems, which may be applicable to a wide range of problems where tissue mechanics is a key factor such as bone remodelling and wound healing.

Funded Activity Details

Start Date: 01-01-2016

End Date: 31-12-2023

Funding Scheme: Discovery Projects

Funding Amount: $368,542.00

Funder: Australian Research Council