Discovery Projects - Grant ID: DP160103812

Funding Activity

Website
http://dataportal.arc.gov.au/NCGP/Web/Grant/Grant/DP160103812

Funding Status
Closed

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Funded Activity Summary

A novel click chemistry approach to identify learning and memory molecules. This project seeks to contribute to a deeper understanding at a molecular level of how memory is stored in neurons. Long-term memories do not form immediately after learning. Initially fragile, they become resistant to disruption through a process known as memory consolidation. In a second process, termed reconsolidation, pre-established memories are updated and re-stored. Both processes depend on protein synthesis, but little is known about the particular sets of proteins that are involved. The project plans to apply a novel biochemical protocol to a newly established transgenic mouse model that allows the visualisation and identification of newly synthesised proteins in the hippocampus, a brain area that is critical in memory formation.

Funded Activity Details

Start Date: 01-01-2016

End Date: 28-02-2019

Funding Scheme: Discovery Projects

Funding Amount: $491,800.00

Funder: Australian Research Council

Research Topics

ANZSRC Field of Research (FoR)

Cellular Nervous System | Proteomics and Intermolecular Interactions (excl. Medical Proteomics) | Biochemistry and Cell Biology | Cell Neurochemistry

ANZSRC Socio-Economic Objective (SEO)

Behaviour and Health | Health Related to Ageing | Expanding Knowledge in the Biological Sciences |

Other Keywords

Behaviour and Health | Biochemistry and Cell Biology | Cell Neurochemistry | Cellular Nervous System | Expanding Knowledge in the Biological Sciences | Health Related to Ageing | Proteomics and Intermolecular Interactions (excl. Medical Proteomics)

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